Preheat and prep: Heat the oven to 425°F (220°C).
Line two sheet pans with parchment for easy cleanup.
Make the buffalo sauce: In a bowl, mix hot sauce, melted butter, olive oil, garlic powder, onion powder, smoked paprika, cayenne, salt, and pepper.
Coat the chicken: Pat chicken breasts dry. Add them to the bowl and toss to coat well. Let sit while you prep the veggies.
Season the veggies: On a sheet pan, toss broccoli, cauliflower, and bell pepper with olive oil, salt, pepper, and garlic powder.
Spread in a single layer.
Arrange the chicken: Place the coated chicken on the second sheet pan, leaving space between pieces for even cooking. Spoon any extra sauce over the top.
Roast: Bake both pans for 18–22 minutes. The veggies should be tender with caramelized edges, and the chicken should reach an internal temperature of 165°F (74°C).
Rest and slice: Transfer chicken to a cutting board and rest 5 minutes.
Slice against the grain into strips or cubes.
Mix the drizzle: Stir ranch or blue cheese with a splash of water until it’s pourable. Add herbs if using.
Assemble: Divide veggies and chicken into 4 meal prep containers. Drizzle a little dressing over the chicken, and save extra for serving.
Cool and store: Let containers cool to room temperature before sealing and refrigerating.